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nrr官网(NRR最新发表即将上线)肠道微生物组:退化和再生之间的平衡微生物群失调与神经炎症之间的关联;新兴基因沉默剂:DNA酶;●微生物群,益生菌治疗与神经再生:针对微生物群策略促进神经再生;

nrr官网(NRR最新发表即将上线)(1)

本期导读

●生物材料应用与神经再生:

神经元纤维支架界面的结构要求;

神经组织培养工具:冷冻凝胶支架

●基因治疗与神经再生:

新兴基因沉默剂:DNA酶;

●微生物群,益生菌治疗与神经再生:

针对微生物群策略促进神经再生;

微生物群失调与神经炎症之间的关联;

肠道微生物组:退化和再生之间的平衡

●视网膜疾病的最新治疗展望:

环状RNA治疗策略;

治疗退行性视网膜疾病神经保护剂的最新进展;

骨髓来源单核干细胞治疗视网膜退变。

综述

Neuroprotective agents effective against radiation damage of central nervous system

对中枢神经系统辐射损伤有效的神经保护剂

Mária Lalkovičová

Neuroprotective effects of naturally sourced bioactive polysaccharides: an update

有神经保护作用的天然生物活性多糖:新观点

Xiao-Lan Xu Song Li Rong Zhang Wei-Dong Le

Alerting effects of light in healthy individuals: a systematic review and meta-analysis

光照对健康人警觉的影响:系统综述与meta分析

Yi-Man Mu Xiao-Dan Huang Sui Zhu Zheng-Fang Hu Kwok-Fai So Chao-Ran Ren Qian Tao

Neuron-fibrous scaffold interfaces in the peripheral nervous system: a perspective on the structural requirements

周围神经系统中的神经元纤维支架界面:对结构要求的看法

Sanaz Behtaj James A. St John Jenny A. K. Ekberg Maksym Rybachuk

Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies

用于再生疗法临床前测试的非人灵长类多能干细胞

Ignacio Rodríguez-Polo Rüdiger Behr

Role of exosomes in the pathogenesis of inflammation in Parkinson’s disease

外泌体在帕金森病炎症反应中的作用

Ke-Lu Li Hong-Yan Huang Hui Ren Xing-Long Yang

Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity

星形胶质细胞保护多巴胺能神经元免受氨基色素神经毒害

Juan Segura-Aguilar Bengt Mannervik José Inzunza Mukesh Varshney Ivan Nalvarte Patricia Muñoz

Intranasal neprilysin rapidly eliminates beta-amyloid plaques but causes plaque compensations: the explanation why the beta-amyloid cascade may fail?

鼻腔内的eprilysin能迅速消除β-淀粉样蛋白斑块,但会引起斑块的补偿:解释为什么β-淀粉样蛋白级联可能失败?

Christian Humpel

Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer's disease

重新利用的抗癌表皮生长因子受体抑制剂:阿尔茨海默病的神经保护作用机制

Heba M. Mansour Hala M. Fawzy Aiman S. El-Khatib Mahmoud M. Khattab

Is there a window of opportunity for the therapeutic use of vitamin D in multiple sclerosis?

维生素D在多发性硬化的治疗中是否存在机会窗口?

Sofia Fernanda Gonçalves Zorzella-Pezavento Luiza Ayumi Nishiyama Mimura Marina Bonifácio Denadai William Danilo Fernandes de Souza Thais Fernanda de Campos Fraga-Silva Alexandrina Sartori

Emerging roles of circular RNAs in retinal diseases

环状RNA在视网膜疾病中的新兴作用

Aneliya Hanineva Karen Sophia Park Joshua J. Wang Margaret M. DeAngelis Michael H. Farkas Sarah X. Zhang

Recent developments of neuroprotective agents for degenerative retinal disorders

治疗退行性视网膜疾病的神经保护剂的最新进展

Kepeng Ou Youjian Li Ling Liu Hua Li Katherine Cox Jiahui Wu Jian Liu Andrew D. Dick

Bone marrow-derived mononuclear stem cells in the treatment of retinal degenerations

骨髓来源单核干细胞治疗视网膜变性

Diego García-Ayuso Johnny Di Pierdomenico David García-Bernal Manuel Vidal-Sanz María P. Villegas-Pérez

观点

Inhibition of central axon regeneration: perspective from chondroitin sulfate proteoglycans in lamprey spinal cord injury

桥接阻断轴突再生的细胞外和细胞内机制:从七鳃鳗脊髓损伤中硫酸软骨素蛋白聚糖的角度

Jianli Hu Li-Qing Jin Michael E. Selzer

Neuronal circuitry reconstruction after stem cell therapy in damaged brain

受损大脑干细胞治疗后的神经元回路重建

Daniel Tornero

N-acetyl-L-leucine: a promising treatment option for traumatic brain injury

N-乙酰-L-亮氨酸:创伤性脑损伤的一种有前途的治疗选择

Chinmoy Sarkar Marta M. Lipinski

Chronic traumatic encephalopathy: genes load the gun repeated concussion pulls the trigger

慢性创伤性脑病:基因装枪,反复震荡扣动扳机

Robert Vink Frances Corrigan

Heme as an inducer of cerebral damage in hemorrhagic stroke: potential therapeutic implications

血红素作为出血性卒中脑损伤的诱导剂:潜在治疗意义

Luiz Ricardo da Costa Vasconcellos Pedro Moreno Pimentel-Coelho

Can we promote neural regeneration through microbiota-targeted strategies? Introducing the new concept of neurobiotics

我们能否通过针对微生物群的策略促进神经再生? 神经生物学的新概念

Celia Herrera-Rincon Julia Murciano-Brea Stefano Geuna

Perspective on the relationship between microbiota dysbiosis and neuroinflammation: probiotics as a treatment option

微生物群失调与神经炎症之间的关系:益生菌作为一种治疗选择

Chiao Ng Zahoor A. Shah

Gut microbiome: a balancing act between degeneration and regeneration

肠道微生物组:退化和再生之间的平衡

Nitin Saksena Matt Keon

Early life stress-induced neuroinflammation and neurological disorders: a novel perspective for research

早期生活应激引起的神经炎症和神经疾病:研究新视角

Clarissa Catale Valeria Carola Maria Teresa Viscomi

The blood-brain barrier models to study Apolipoprotein E genotypes in Alzheimer’s disease

用于研究阿尔茨海默病中载脂蛋白 E 基因型的血脑屏障模型

Irundika HK Dias Rachelle Taiwo Dan Ma

Endocannabinoid metabolism and Alzheimer’s disease

内源性大麻素代谢与阿尔茨海默病

Chu Chen

Glucose metabolism in amyotrophic lateral sclerosis: it is bitter-sweet

肌萎缩侧索硬化中的葡萄糖代谢:苦乐参半

Titaya Lerskiatiphanich Jianina Marallag John D. Lee

K /Cl− co-transporter-2 upmodulation: a multi-modal therapy to treat spinal cord injury

钾氯共转运体2上调:一种治疗脊髓损伤的多模式疗法

Shane V. Hegarty Joanna Stanicka

Opportunities for agent based modeling of retinal stem cell transplantation

基于代理的视网膜干细胞移植建模机会

Larissa M. DePamphilis Troy Shinbrot Maribel Vazquez

Cryogel scaffolds: soft and easy to use tools for neural tissue culture

冷冻凝胶支架:柔软且易于使用的神经组织培养工具

Ben Newland Katherine R. Long

DNAzyme as a rising gene-silencing agent in theranostic settings

DNA酶作为一种新兴的基因沉默剂在治疗领域的应用

Nan Zhang

研究原著

脑损伤与神经再生

Stellate ganglion block reduces inflammation and improves neurological function in diabetic rats during ischemic stroke

星状神经节阻滞有助于改善糖尿病缺血性脑卒中的神经功能及炎症反应

Ting-Ting Li Qiang Wan Xin Zhang Yuan Xiao Li-Ying Sun Yu-Rong Zhang Xiang-Nan Liu Wan-Chao Yang

Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice

低强度经颅聚焦超声刺激保护脑缺血后血脑屏障的完整性

Li-Dong Deng Lin Qi Qian Suo Sheng-Ju Wu Muyassar Mamtilahun Ru-Bing Shi Ze Liu Jun-Feng Sun Yao-Hui Tang Zhi-Jun Zhang Guo-Yuan Yang Ji-Xian Wang

Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice

尿石素A可减轻创伤性脑损伤后血脑屏障破坏及神经元凋亡

Qiu-Yuan Gong Lin Cai Yao Jing Wei Wang Dian-Xu Yang Shi-Wen Chen Heng-Li Tian

脊髓损伤与神经再生

MicroRNA-101a-3p mimic ameliorates spinal cord ischemia/reperfusion injury

microRNA-101a-3p模拟物可减轻脊髓缺血再灌注损伤

Zai-Li Zhang Dan Wang Feng-Shou Chen

Nerve root magnetic stimulation improves locomotor function following spinal cord injury with electrophysiological improvements and cortical synaptic reconstruction

新型上行神经调控:神经根磁刺激促进电生理修复和皮质突触重建改善脊髓损伤后的运动功能

Ya Zheng Dan Zhao Dong-Dong Xue Ye-Ran Mao Ling-Yun Cao Ye Zhang Guang-Yue Zhu Qi Yang Dong-Sheng Xu

Ruxolitinib attenuates secondary injury after traumatic spinal cord injury

芦可替尼可降低创伤性脊髓损伤后的继发性病变

Zhan-Yang Qian Ren-Yi Kong Sheng Zhang Bin-Yu Wang Jie Chang Jiang Cao Chao-Qin Wu Zi-Yan Huang Ao Duan Hai-Jun Li Lei Yang Xiao-Jian Cao

周围神经损伤与神经再生

The proteome of distal nerves: implication in delayed repair and poor functional recovery

远端神经蛋白质组在延迟修复和不良功能恢复中的意义

Song Guo Raymond M. Moore M. Cristine Charlesworth Kenneth L. Johnson Robert J. Spinner Anthony J. Windebank Huan Wang

Sustained delivery of vascular endothelial growth factor mediated by bioactive methacrylic anhydride hydrogel accelerates peripheral nerve regeneration after crush injury

持续释放血管内皮生长因子的甲基丙烯酸酐化明胶水凝胶可加速挤压损伤周围神经的再生

Wanlin Xu Yifan Wu Hao Lu Yun Zhu Jinhai Ye Wenjun Yang

Sustained release of exosomes loaded into polydopamine-modified chitin conduits promotes peripheral nerve regeneration in rats

聚多巴胺修饰甲壳质小间隙神经套管负载外泌体缓慢释放可促进周围神经的再生

Ci Li Song-Yang Liu Meng Zhang Wei Pi Bo Wang Qi-Cheng Li Chang-Feng Lu Pei-Xun Zhang

Delivery of nitric oxide-releasing silica nanoparticles for in vivo revascularization and functional recovery after acute peripheral nerve crush injury

释放一氧化氮的硅纳米颗粒促进急性周围神经压迫损伤后血管重建和功能恢复

Jung Il Lee Ji Hun Park Yeong-Rim Kim Kihak Gwon Hae Won Hwang Gayoung Jung Joo-Yup Lee Jeong-Yun Sun Jong Woong Park Jae Ho Shin Myoung-Ryul Ok

神经退行性疾病与神经再生

(D-Ser2) oxyntomodulin recovers hippocampal synaptic structure and theta rhythm in Alzheimer’s disease transgenic mice

(D-Ser2)胃泌酸调节素可恢复阿尔茨海默病转基因小鼠的海马突触功能及theta节律

Guang-Zhao Yang Qi-Chao Gao Wei-Ran Li Hong-Yan Cai Hui-Min Zhao Jian-Ji Wang Xin-Rui Zhao Jia-Xin Wang Mei-Na Wu Jun Zhang Christian Hölscher Jin-Shun Qi Zhao-Jun Wang

Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer’s disease

水通道蛋白 4 缺失可抵消自主运动对阿尔茨海默病模型的有益影响

Yun Liu Pan-Pan Hu Shuang Zhai Wei-Xi Feng Rui Zhang Qian Li Charles Marshall Ming Xiao Ting Wu

Abnormal characterization of dynamic functional connectivity in Alzheimer’s disease

阿尔茨海默病动态功能连接的异常表征

Cui Zhao Wei-Jie Huang Feng Feng Bo Zhou Hong-Xiang Yao Yan-E Guo Pan Wang Lu-Ning Wang Ni Shu Xi Zhang

nrr官网(NRR最新发表即将上线)(2)

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