有机合成的ppt(有机合成第一章)
有机合成的ppt(有机合成第一章)3.计算机技术的应用,最初是在文献搜索领域,但最近作为对复杂有机分子合成路线设计的宝贵帮助。1.制备,分离和纯化技术,适用于从毫克到千克数量的反应物和产物。2.用于对纯化合物进行结构表征的化学程序,以及各种光谱方法的常规应用。3.新试剂和反应程序的范围不断扩大,由于其更高的特异性或更高的使用安全性,它们可能会取代旧方法。大量的理论思想使人们能够根据反应机理以及适当的立体化学因素来理解化合物之间的相互作用方式。
The synthesis of organic componds is traditionally an important part of the training of an organic chemist.By undertaking the preparation of a varied range of compounds and using a representative selection of reaction processes and techniques the prospective organic chemist becomes familiar with the chemical and physical properties of organic substances and begins to understand more clearly the factors which govern their reactivity .The discussion sections which are sited before the relevant expermental procedures provide a bridge between laboratory work and lecture material .Thus while the synthnesis of quite simple compounds is of considerable educational value particularly if the reactions involved are of a general nature wider reading of a selection of the excellent review articles that are cited at the ends of chapters should enable the advanced student of organic chemistry to appreciate the wider qmplications of the reactions under consideration.
The student will become increasingly aware during the early years of training of the very great range of concepts and techniques with which the practising organic chemist has to be familiar .Some of these may be summarised as follows :
- The preparative isolation amd purification techniques which are applicable to quantities of reactants and products from milligram to kilogram amounts.
- The chemical procedures which are used for the structural characterisation of pure compounds together with the routine application of the various spectroscopic methods.
- The ever-increasing range of new reagents and reaction procedures which may replace older methods by reason of their greater specificity or increased safety in use .
- The enormous body of theoretical ideas which enable the manner in which compounds interact to be understood in terms of the reaction mechanism and if appropriate stereochemical factors.
- The application of computer techniques initially in the area of literature searching but more recently as an invaluable aid to the design of synthetic routes to complex organic molecules.
传统上,有机化合物的合成是有机化学家培训的重要组成部分。通过进行各种化合物的制备,并使用代表性的反应过程和技术选择,准有机化学家逐渐熟悉化学和化学反应。有机物质的物理性质,并开始更清楚地了解影响其反应性的因素。相关实验程序之前的讨论部分提供了实验室工作和讲义材料之间的桥梁。因此,相当简单的化合物的合成是相当重要的具有教育意义,特别是如果涉及的反应具有一般性,请更广泛地阅读本章结尾处所引用的精选评论文章,应使有机化学的高级学员能够体会到在以下条件下反应的更广泛意义考虑。
在早期的培训过程中,学生将逐渐认识到有机化学从业人员必须熟悉的各种概念和技术。其中一些可以总结如下:
1.制备,分离和纯化技术,适用于从毫克到千克数量的反应物和产物。
2.用于对纯化合物进行结构表征的化学程序,以及各种光谱方法的常规应用。
3.新试剂和反应程序的范围不断扩大,由于其更高的特异性或更高的使用安全性,它们可能会取代旧方法。大量的理论思想使人们能够根据反应机理以及适当的立体化学因素来理解化合物之间的相互作用方式。
3.计算机技术的应用,最初是在文献搜索领域,但最近作为对复杂有机分子合成路线设计的宝贵帮助。